Trityl Candesartan Cilexetil CAS 170791-09-0 Purity >98.0% (HPLC) Factory

Short Description:

Chemical Name: Trityl Candesartan Cilexetil 

CAS: 170791-09-0

Purity: >98.0% (HPLC) 

Appearance: White to Off-White Crystalline Powder 

Intermediate of Candesartan Cilexetil (CAS: 145040-37-5)

Contact: Dr. Alvin Huang    

Mobile/Wechat/WhatsApp: +86-15026746401  

E-Mail: alvin@ruifuchem.com


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Description:

170791-09-0 - Chemical Properties:

Chemical Name Trityl Candesartan Cilexetil
Synonyms N-Tritylcandesartan Cilexetil; Candesartan Cilexetil EP Impurity H; Candesartan Cilexetil N1-Trityl Analog; 2-Ethoxy-1-[[2'-[1-(Triphenylmethyl) -1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-Benzimidazole-7-Carboxylic Acid 1-[[(cyclohexyloxy) carbonyl]oxy]ethyl Ester
CAS Number 170791-09-0
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C52H48N6O6
Molecular Weight 852.97
Density 1.26±0.10 g/cm3
Melting Point 176.0~178.0℃(dec.)
COA & MSDS Available
Place of Origin  Shanghai, China
Brand Ruifu Chemical

170791-09-0 - Specifications:

Item Specifications
Appearance White to Off-White Crystalline Powder
Purity / Analysis Method >98.0% (HPLC) 
Melting Point 176.0~178.0℃
Loss on Drying <1.00%
Residue on Ignition <0.50%
Heavy Metals <20ppm
Total Impurities <2.00% 
Test Standard Enterprise Standard
Usage Impurity / Intermediate of Candesartan Cilexetil (CAS 145040-37-5)

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

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170791-09-0 - Application:

Trityl Candesartan Cilexetil (CAS: 170791-09-0) is an impurity / intermediate of Candesartan Cilexetil (CAS 145040-37-5). Trityl Candesartan Cilexetil is an advanced intermediate used in the preparation of the prodrug Candesartan Cilexetil, an angiotension II receptor antagonist, used in the treatment of hypertension. Candesartan is an angiotensin II receptor antagonist with IC50 of 0.26 nM. Target: Angiotensin II Receptor candesartan is indicated for the treatment of hypertension. Candesartan Cilexetil is used clinical for receptor antagonist of angiotensin AT1, has good effect to the different degree of hypertension patients who used other antihypertensive drugs without efficacy, is a new generation of highly efficient antihypertensive drugs. 

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